diff --git a/changes/3580.bugfix.md b/changes/3580.bugfix.md
new file mode 100644
index 0000000000..48a492bd16
--- /dev/null
+++ b/changes/3580.bugfix.md
@@ -0,0 +1 @@
+Fix `ZipStore` leaving duplicate entries in the zip central directory when array metadata is written more than once (e.g. after `resize()`). The central directory is now deduplicated on `close()`, keeping only the most recent entry for each filename.
diff --git a/src/zarr/storage/_zip.py b/src/zarr/storage/_zip.py
index 72bf9e335a..cc6754a790 100644
--- a/src/zarr/storage/_zip.py
+++ b/src/zarr/storage/_zip.py
@@ -4,6 +4,7 @@
 import shutil
 import threading
 import time
+import warnings
 import zipfile
 from pathlib import Path
 from typing import TYPE_CHECKING, Any, Literal
@@ -122,8 +123,36 @@ def close(self) -> None:
         # docstring inherited
         super().close()
         with self._lock:
+            self._dedup_central_directory()
             self._zf.close()
 
+    def _dedup_central_directory(self) -> None:
+        """Remove duplicate entries from the zip central directory.
+
+        When an array is resized or metadata is updated multiple times, ZipStore
+        writes a new entry for the same key each time (ZIP files are append-only).
+        This leaves duplicate filenames in the central directory, which confuses
+        many zip readers and wastes space.  Before closing, we keep only the
+        *last* (most recent) entry for every filename so that the on-disk central
+        directory is clean.
+
+        ``NameToInfo`` is already a ``{filename: latest_ZipInfo}`` mapping because
+        each ``writestr``/``write`` call does ``NameToInfo[name] = zinfo``, so
+        later writes overwrite earlier ones.  We therefore only need to rebuild
+        ``filelist`` from the values of ``NameToInfo``; ``NameToInfo`` itself
+        requires no update.
+
+        The new list is computed before being assigned so that the ZipFile object
+        is never left in an inconsistent state if an exception is raised.
+        """
+        if self._zf.mode not in ("w", "a", "x"):
+            return
+        # namelist() and getinfo() are public API.
+        # dict.fromkeys preserves first-seen order while deduplicating names;
+        # getinfo() returns the latest ZipInfo for each name (NameToInfo[name]).
+        unique_names = dict.fromkeys(self._zf.namelist())
+        self._zf.filelist = [self._zf.getinfo(name) for name in unique_names]
+
     async def clear(self) -> None:
         # docstring inherited
         with self._lock:
@@ -205,7 +234,12 @@ def _set(self, key: str, value: Buffer) -> None:
             keyinfo.external_attr |= 0x10  # MS-DOS directory flag
         else:
             keyinfo.external_attr = 0o644 << 16  # ?rw-r--r--
-        self._zf.writestr(keyinfo, value.to_bytes())
+        # ZIP files are append-only; writing an existing key creates a second entry.
+        # We intentionally allow this and remove duplicates in _dedup_central_directory()
+        # when the store is closed.
+        with warnings.catch_warnings():
+            warnings.simplefilter("ignore", UserWarning)
+            self._zf.writestr(keyinfo, value.to_bytes())
 
     async def set(self, key: str, value: Buffer) -> None:
         # docstring inherited
diff --git a/tests/test_store/test_zip.py b/tests/test_store/test_zip.py
index 744ee82945..08560ed685 100644
--- a/tests/test_store/test_zip.py
+++ b/tests/test_store/test_zip.py
@@ -152,3 +152,28 @@ async def test_move(self, tmp_path: Path) -> None:
         assert destination.exists()
         assert not origin.exists()
         assert np.array_equal(array[...], np.arange(10))
+
+    def test_no_duplicate_entries_after_resize(self, tmp_path: Path) -> None:
+        # Regression test for https://github.com/zarr-developers/zarr-python/issues/3580
+        # Resizing an array (which rewrites zarr.json) used to leave duplicate
+        # filenames in the zip central directory.
+        zip_path = tmp_path / "data.zip"
+        store = ZipStore(zip_path, mode="w")
+        arr = zarr.create_array(store, shape=(5,), chunks=(5,), dtype="i4")
+        arr[:] = np.arange(5)
+
+        # Resize triggers metadata rewrite, producing a second zarr.json entry
+        arr.resize((10,))
+        arr[5:] = np.arange(5, 10)
+        store.close()
+
+        # Verify no duplicate filenames in the central directory
+        with zipfile.ZipFile(zip_path, "r") as zf:
+            names = [info.filename for info in zf.infolist()]
+        assert len(names) == len(set(names)), f"Duplicate entries found: {names}"
+
+        # Verify data integrity
+        store2 = ZipStore(zip_path, mode="r")
+        arr2 = zarr.open_array(store2)
+        assert arr2.shape == (10,)
+        assert np.array_equal(arr2[:], np.arange(10))