diff --git a/Spanner/src/Database.php b/Spanner/src/Database.php
index 477c4d65429b..94f864c3672f 100644
--- a/Spanner/src/Database.php
+++ b/Spanner/src/Database.php
@@ -115,6 +115,7 @@ class Database
     public const TYPE_JSON = TypeCode::JSON;
     public const TYPE_PG_OID = 'pgOid';
     public const TYPE_INTERVAL = TypeCode::INTERVAL;
+    public const TYPE_UUID = TypeCode::UUID;
 
     private Operation $operation;
     private IamManager|null $iam = null;
diff --git a/Spanner/src/SpannerClient.php b/Spanner/src/SpannerClient.php
index 5d3e6a0c5349..b751f01179fa 100644
--- a/Spanner/src/SpannerClient.php
+++ b/Spanner/src/SpannerClient.php
@@ -873,6 +873,26 @@ public function pgOid(string|null $value): PgOid
         return new PgOid($value);
     }
 
+    /**
+     * Create a UUID object.
+     *
+     * The string value must consists of 32 hexadecimal digits in five groups separated
+     * by hyphens in the form 8-4-4-4-12. The hexadecimal digits represent 122
+     * random bits and 6 fixed bits, in compliance with RFC 4122 section 4.4.
+     *
+     * Example:
+     * ```
+     * $uuid = $spanner->uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479');
+     * ```
+     *
+     * @param string $value The UUID value.
+     * @return Uuid
+     */
+    public function uuid(string $value): Uuid
+    {
+        return new Uuid($value);
+    }
+
     /**
      * Create an Int64 object. This can be used to work with 64 bit integers as
      * a string value while on a 32 bit platform.
diff --git a/Spanner/src/Uuid.php b/Spanner/src/Uuid.php
new file mode 100644
index 000000000000..0a7cd038198a
--- /dev/null
+++ b/Spanner/src/Uuid.php
@@ -0,0 +1,95 @@
+<?php
+/**
+ * Copyright 2025 Google LLC
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+namespace Google\Cloud\Spanner;
+
+/**
+ * Represents a value with a data type of
+ * [UUID](https://cloud.google.com/spanner/docs/reference/standard-sql/data-types#uuid_type).
+ *
+ * Example:
+ * ```
+ * use Google\Cloud\Spanner\SpannerClient;
+ *
+ * $spanner = new SpannerClient(['projectId' => 'my-project']);
+ *
+ * $uuid = $spanner->uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479');
+ * ```
+ */
+class Uuid implements ValueInterface
+{
+    /**
+     * @var string
+     */
+    private $value;
+
+    /**
+     * @param string $value The UUID value.
+     * @throws \InvalidArgumentException
+     */
+    public function __construct(string $value)
+    {
+        // Canonical UUID format: 8-4-4-4-12 hex digits
+        $pattern = '/^[0-9a-fA-F]{8}-[0-9a-fA-F]{4}-[0-9a-fA-F]{4}-[0-9a-fA-F]{4}-[0-9a-fA-F]{12}$/';
+        if (!preg_match($pattern, $value)) {
+            throw new \InvalidArgumentException(
+                'Invalid UUID format. Expected canonical hexadecimal format: xxxxxxxx-xxxx-xxxx-xxxx-xxxxxxxxxxxx'
+            );
+        }
+        $this->value = strtolower($value);
+    }
+
+    /**
+     * Get the underlying value.
+     *
+     * @return string
+     */
+    public function get(): string
+    {
+        return $this->value;
+    }
+
+    /**
+     * Get the type.
+     *
+     * @return int
+     */
+    public function type(): int
+    {
+        return Database::TYPE_UUID;
+    }
+
+    /**
+     * Format the value as a string.
+     *
+     * @return string
+     */
+    public function formatAsString(): string
+    {
+        return $this->value;
+    }
+
+    /**
+     * Format the value as a string.
+     *
+     * @return string
+     */
+    public function __toString()
+    {
+        return $this->value;
+    }
+}
diff --git a/Spanner/src/ValueMapper.php b/Spanner/src/ValueMapper.php
index 16cad27973a5..83e9ba965bce 100644
--- a/Spanner/src/ValueMapper.php
+++ b/Spanner/src/ValueMapper.php
@@ -48,6 +48,7 @@ class ValueMapper
     const TYPE_JSON = TypeCode::JSON;
     const TYPE_PROTO = TypeCode::PROTO;
     const TYPE_INTERVAL = TypeCode::INTERVAL;
+    const TYPE_UUID = TypeCode::UUID;
     const TYPE_PG_NUMERIC = 'pgNumeric';
     const TYPE_PG_JSONB = 'pgJsonb';
     const TYPE_PG_OID = 'pgOid';
@@ -74,6 +75,7 @@ class ValueMapper
         self::TYPE_FLOAT32,
         self::TYPE_PROTO,
         self::TYPE_INTERVAL,
+        self::TYPE_UUID,
     ];
 
     /*
@@ -386,6 +388,9 @@ private function decodeValue(mixed $value, array $type): mixed
                 }
                 $value = Interval::parse($value);
                 break;
+            case self::TYPE_UUID:
+                $value = new Uuid($value);
+                break;
         }
 
         return $value;
diff --git a/Spanner/tests/System/WriteTest.php b/Spanner/tests/System/WriteTest.php
index ef0d17979fa9..5efd7b02d3c5 100644
--- a/Spanner/tests/System/WriteTest.php
+++ b/Spanner/tests/System/WriteTest.php
@@ -80,6 +80,8 @@ public static function setUpTestFixtures(): void
                 stringField STRING(MAX),
                 timestampField TIMESTAMP,
                 numericField NUMERIC,
+                uuidField STRING(36),
+                arrayUuidField ARRAY<STRING(36)>,
                 protoField `testing.data.User`,
             ) PRIMARY KEY (id)',
             'CREATE TABLE ' . self::COMMIT_TIMESTAMP_TABLE_NAME . ' (
@@ -108,7 +110,8 @@ public function fieldValueProvider()
             [$this->randId(), 'intField', 787878787],
             [$this->randId(), 'stringField', 'foo bar'],
             [$this->randId(), 'timestampField', new Timestamp(new \DateTime())],
-            [$this->randId(), 'numericField', new Numeric('0.123456789')]
+            [$this->randId(), 'numericField', new Numeric('0.123456789')],
+            [$this->randId(), 'uuidField', new Uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479')]
         ];
     }
 
@@ -136,7 +139,7 @@ public function testWriteAndReadBackValue($id, $field, $value)
         $read = $db->read(self::TABLE_NAME, $keyset, [$field]);
         $row = $read->rows()->current();
 
-        if ($value instanceof Timestamp) {
+        if ($value instanceof Timestamp || $value instanceof Uuid) {
             $this->assertEquals($value->formatAsString(), $row[$field]->formatAsString());
         } else {
             $this->assertValues($value, $row[$field]);
@@ -150,7 +153,7 @@ public function testWriteAndReadBackValue($id, $field, $value)
         ]);
 
         $row = $exec->rows()->current();
-        if ($value instanceof Timestamp) {
+        if ($value instanceof Timestamp || $value instanceof Uuid) {
             $this->assertEquals($value->formatAsString(), $row[$field]->formatAsString());
         } elseif ($value instanceof Message) {
             $this->assertInstanceOf(Proto::class, $row[$field]);
@@ -305,6 +308,11 @@ public function arrayFieldValueProvider()
                 new User(['name' => 'User 1']),
                 new User(['name' => 'User 2']),
             ]],
+            [$this->randId(), 'arrayUuidField', [
+                new Uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479'),
+                new Uuid('a47ac10b-58cc-4372-a567-0e02b2c3d479')
+            ]],
+            [$this->randId(), 'arrayUuidField', null],
         ];
     }
 
diff --git a/Spanner/tests/Unit/UuidTest.php b/Spanner/tests/Unit/UuidTest.php
new file mode 100644
index 000000000000..6a0a363f1dfc
--- /dev/null
+++ b/Spanner/tests/Unit/UuidTest.php
@@ -0,0 +1,55 @@
+<?php
+/**
+ * Copyright 2025 Google LLC
+ *
+ * Licensed under the Apache License, Version 2.0 (the "License");
+ * you may not use this file except in compliance with the License.
+ * You may obtain a copy of the License at
+ *
+ *      http://www.apache.org/licenses/LICENSE-2.0
+ *
+ * Unless required by applicable law or agreed to in writing, software
+ * distributed under the License is distributed on an "AS IS" BASIS,
+ * WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
+ * See the License for the specific language governing permissions and
+ * limitations under the License.
+ */
+
+namespace Google\Cloud\Spanner\Tests\Unit;
+
+use Google\Cloud\Spanner\Database;
+use Google\Cloud\Spanner\Uuid;
+use PHPUnit\Framework\TestCase;
+
+/**
+ * @group spanner
+ */
+class UuidTest extends TestCase
+{
+    public function testUuid()
+    {
+        $val = 'f47ac10b-58cc-4372-a567-0e02b2c3d479';
+        $uuid = new Uuid($val);
+
+        $this->assertEquals($val, $uuid->get());
+        $this->assertEquals($val, (string) $uuid);
+        $this->assertEquals($val, $uuid->formatAsString());
+        $this->assertEquals(Database::TYPE_UUID, $uuid->type());
+    }
+
+    public function testUuidLowercase()
+    {
+        $val = 'F47AC10B-58CC-4372-A567-0E02B2C3D479';
+        $uuid = new Uuid($val);
+
+        $this->assertEquals(strtolower($val), $uuid->get());
+    }
+
+    public function testInvalidUuid()
+    {
+        $this->expectException(\InvalidArgumentException::class);
+        $this->expectExceptionMessage('Invalid UUID format');
+
+        new Uuid('invalid-uuid');
+    }
+}
diff --git a/Spanner/tests/Unit/ValueMapperTest.php b/Spanner/tests/Unit/ValueMapperTest.php
index b2cf74c87213..fe4247c42fd1 100644
--- a/Spanner/tests/Unit/ValueMapperTest.php
+++ b/Spanner/tests/Unit/ValueMapperTest.php
@@ -34,6 +34,7 @@
 use Google\Cloud\Spanner\V1\TypeAnnotationCode;
 use Google\Cloud\Spanner\V1\TypeCode;
 use Google\Cloud\Spanner\ValueMapper;
+use Google\Cloud\Spanner\Uuid;
 use PHPUnit\Framework\TestCase;
 use Testing\Data\Book;
 use Testing\Data\User;
@@ -73,7 +74,8 @@ public function simpleTypes()
             [1, Database::TYPE_INT64],
             ['john', Database::TYPE_STRING],
             [3.1415, Database::TYPE_FLOAT64],
-            [false, Database::TYPE_BOOL]
+            [false, Database::TYPE_BOOL],
+            [new Uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479'), Database::TYPE_UUID]
         ];
     }
 
@@ -858,7 +860,8 @@ public function simpleTypeValues()
             [new Bytes('hello world'), base64_encode('hello world')],
             [new Proto('hello world', 'foo'), 'hello world'],
             [['foo', 'bar']],
-            ['{\"rating\":9,\"open\":true}']
+            ['{\"rating\":9,\"open\":true}'],
+            [new Uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479'), 'f47ac10b-58cc-4372-a567-0e02b2c3d479']
         ];
     }
 
@@ -1379,4 +1382,53 @@ public function provideFloatTypes()
             [Database::TYPE_FLOAT32]
         ];
     }
+
+    public function testDecodeValuesUuid()
+    {
+        $uuid = 'f47ac10b-58cc-4372-a567-0e02b2c3d479';
+        $res = $this->mapper->decodeValues(
+            $this->createField(Database::TYPE_UUID),
+            $this->createRow($uuid),
+            Result::RETURN_ASSOCIATIVE
+        );
+        $this->assertInstanceOf(Uuid::class, $res['rowName']);
+        $this->assertEquals($uuid, $res['rowName']->get());
+    }
+
+    public function testFormatParamsForExecuteSqlArrayUuid()
+    {
+        $uuid = new Uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479');
+        $params = [
+            'array' => [$uuid]
+        ];
+
+        $res = $this->mapper->formatParamsForExecuteSql($params);
+
+        $this->assertEquals($uuid->get(), $res['params']['array'][0]);
+        $this->assertEquals(Database::TYPE_ARRAY, $res['paramTypes']['array']['code']);
+        $this->assertEquals(Database::TYPE_UUID, $res['paramTypes']['array']['arrayElementType']['code']);
+    }
+
+    public function testFormatParamsForExecuteSqlStructUuid()
+    {
+        $uuid = new Uuid('f47ac10b-58cc-4372-a567-0e02b2c3d479');
+        $params = [
+            'struct' => [
+                'uuid' => $uuid
+            ]
+        ];
+        $types = [
+            'struct' => (new StructType())
+                ->add('uuid', Database::TYPE_UUID)
+        ];
+
+        $res = $this->mapper->formatParamsForExecuteSql($params, $types);
+
+        $this->assertEquals($uuid->get(), $res['params']['struct'][0]);
+        $this->assertEquals(Database::TYPE_STRUCT, $res['paramTypes']['struct']['code']);
+        $this->assertEquals(
+            Database::TYPE_UUID,
+            $res['paramTypes']['struct']['structType']['fields'][0]['type']['code']
+        );
+    }
 }