Add Significance to Mitocheck Spearman ranking correlation.

[axiomcura]

Had a discussion with @wli51 about how to incorporate significance into the Mitocheck results.

We narrowed it down to two approaches:

1. Generate a delta heatmap to quantify how much the rank-based rho scores deviate from those obtained under shuffled data.
2. Perform a bootstrap analysis using the shuffled rho (rank) scores to construct a null distribution, and then compare the observed rank scores for each phenotype against this distribution to assess significance.

This will help us understand two things: even if some signals appear weak, we can determine whether they are statistically significant.